RAF Typhoon fighter aircraft have joined forces with French aircraft in a combined operation against an subterranean weapons facility in Syria used by the IS group, per a report from the UK's MoD.
The location, located using surveillance, was assessed as storing arms and explosives, the release indicated, and was situated in hills just above Palmyra in Syria's central region.
"The RAF jets utilized precision-guided Paveway IV munitions to strike a number of approach shafts leading to the depot... initial indications suggest the objective was successfully hit," the MoD said.
There was no indication of any civilian casualties in the operation on Saturday evening and all the aircraft returned safely, the defence officials confirmed.
The British jets were supported by a Voyager aerial refuelling aircraft.
Daesh - also known as the so-called Islamic State - established jihadist rule over significant areas in Syria and Iraq until 2019.
"This operation demonstrates our UK leadership, and resolve to stand shoulder to shoulder with our partners, to eradicate any resurgence of Daesh and their violent and radical beliefs in the region," UK Defence Secretary the Defence Secretary said.
UK warplanes have conducted overwatch operations over Syrian airspace to "deter any attempted comeback" of IS following its defeat at the Baghuz confrontation in the year 2019, the authorities noted.
"I want to thank the personnel of the UK armed forces who took part in this strike for their expertise and their courage," Healey added. "Including them were a great many UK service members deployed over the holidays. This action, to eliminate dangerous terrorists who pose a risk to our way of life, highlights how British military are always on standby, all year round, keeping Britain secure domestically and powerful internationally."
Last December, the United States armed forces conducted what it termed a "massive strike" against Daesh sites in Syria, after an ambush killed two US servicemembers and a civilian linguist in Palmyra.
The United Nations estimates Islamic State still boasts between 5,000 and 7,000 fighters in both countries.